Component resolved diagnostics in allocation to specific immunotherapy
نویسندگان
چکیده
منابع مشابه
Component-resolved diagnosis to optimize allergen-specific immunotherapy in the Mediterranean area.
Allergen-specific immunotherapy (SIT) is the only allergen-specific treatment for allergy. It can prevent progression of the disease and has a long-lasting therapeutic effect. Since SIT is allergen-specific, the identification of the disease-eliciting allergen is an essential prerequisite for the accurate prescription of treatment. Diagnostic tests based on allergen extracts consist of mixtures...
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PURPOSE OF REVIEW Component-resolved diagnostics makes use of defined allergen molecules to analyse IgE-mediated sensitizations at a molecular level. Here, we review recent studies on the use of component-resolved diagnostics in the field of Hymenoptera venom allergy (HVA) and discuss its benefits and limitations. RECENT FINDINGS Component resolution in HVA has moved from single molecules to ...
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© Copyright The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://e-aair.org The gold standard for the diagnosis of IgE-mediated food allergy is an oral food challenge (OFC) that directly verifies the causal relationship between clinical symptoms and offending foods. However, OFC carries a risk of developing fatal ...
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INTRODUCTION As replacement for the oral food challenge, decision-points for sensitization test have been established, but suboptimal sensitivity and/or specificity, as well as regional differences, have reduced the clinical usability. IgE toward specific peanut protein components has been reported to be of value, but data on correlation with clinical data are sparse. Our aim was to correlate I...
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Allergen specific immunotherapy remains the only means to change the natural history of allergic disease. Thanks to the recent advances in molecular biology a large spectrum of purified allergen molecules are presently routinely available for diagnostic purposes. This review represents a practical guide on how to use these new diagnostic tools in order to detect precisely the primary sensitizin...
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ژورنال
عنوان ژورنال: Alergologia Polska - Polish Journal of Allergology
سال: 2019
ISSN: 2353-3854
DOI: 10.5114/pja.2019.91218